Diamond MIX-A Mustang

Description

Download

Reviews

1. Introduction

Ion exchange (IEX) chromatography is a very effective method for the separation and purification of biomolecule. The method mainly relies on the interaction between positive and negative charges, and uses the charge properties and differences of different biological molecules under specific conditions to separate them. It has the characteristics of high load, good resolution, controllable condition and easy scale-up. It has been widely used in medicine, chemical industry, metallurgy, food and other fields.

However, when doing ion exchange chromatography, the salt content in the sample should not be too high. The mixed-mode ion exchange resin has a certain salt tolerance by introducing benzene ring on the ligand, which eliminates the desalting step of high salt samples and expands the application range of ion exchange.

IEX resin is composed of three parts: (1)Cross-linked agarose matrix, that has the characteristics of porousness, hydrophobicity and good chemical stability. Diamond matrix is high rigidity agarose matrix, which is chemically modified and modified from the traditional Bestarose 6FF matrix, with better mechanical properties. (2)The functional group fixed on the base matrix, it is a mixed-mode charged groups, usually by the charge part and hydrophobic part of two parts. (3)An ion that is oppositely charged to a functional group (can be called a counter ion), which can be reversibly bond to a functional group.

Diamond MIX-A Mustang is a mixed-mode strong anion exchange resin which is formed by coupling Phenyl glycidyl ether functional groups and 2,3-epoxypropyltrimethylammonium chloride functional groups to the high-rigidity agarose microspheres with smaller particles through two steps of crosslinking.

2. Technical Characteristics

Appearance	White slurry
Matrix	High rigidity agarose
Functional group	Compound strong anion group
Average particle size+	36~44μm
Ionic capacity	80~110μmol Cl^-/mL packed resin
Max. pressure	0.5 MPa
Pressure flow velocity	≥450cm/h（0.5MPa BXK 100/500 H=20cm 20℃）
Chemical Stability	Stable in common aqueous buffers: 1M NaOH++,1M HAc++, 2M NaCl, 30% isopropyl alcohol, 70% ethanol Avoid contact with oxidizing agents, cationic detergents.
pH stability	2~14 (CIP), 3~12(working)
Operating temperature	Operating temperature:2~40℃, do not freeze
Storage⁺⁺⁺	2~30℃, 20% ethanol or 2% benzyl alcohol
Recommend flow velocity	100-300cm/h

+ Average particle size is the accumulated resin particle size of packing volume distribution.

++1M NaOH and 1M HAc only be used for cleaning.

+++2% benzyl alcohol is only used for international transport or special requirements from customer.

3. Order Information

Product	Cat. No.	Pack size
Diamond MIX-A Mustang	AI0151	25mL
	AI0152	100mL
	AI306211	500mL
	AI0153	1L
	AI0154	5L
	AI0155	10L
	AI306215	20L
	AI306216	40L

Prepacked columns	Cat. No.	Pack size
EzFast MIX-A Mustang	EI01521	1×1mL
	EI306251	5×1mL
	EI306203	1×5mL
	EI306253	5×5mL
EzScreen MIX-A Mustang	EI01525	1×4.9mL
EzScreen MIX-A Mustang	EI01535	5×4.9mL
EzLoad 16/10 MIX-A Mustang	EI306204	1 pcs
EzLoad 26/10 MIX-A Mustang	EI306206	1 pcs

Share your thoughts Showing

Your rating

Your review *

Name *

Email *

Submit

MIX-A Resins