Diamond SP Mustang XL

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1. Introduction

Ion exchange chromatography(IEC)is a very effective method for the separation and purification of biomolecule. The method mainly relies on the interaction between positive and negative charges, and uses the charge properties and differences of different biological molecules under specific conditions to separate them. It has the characteristics of high load, good resolution, controllable condition and easy scale-up. It has been widely used in medicine, chemical industry, metallurgy, food and other fields.

IEC resin is composed of three parts: (1)Cross-linked agarose matrix, that has the characteristics of porous, hydrophilic and good chemical stability; through the modification to traditional agarose molecules, it has stronger mechanical properties, which is called high rigid agarose, namely Diamond matrix; (2)Functional groups fixed to the matrix, which are electrically charged groups, determine the properties of the IEC resin; (3)An ion (called an equilibrium ion) that has an opposite charge to the functional group and can be reversibly bound to the functional group.

Diamond SP Mustang XL is a high-rigidity agarose microsphere first coupled with dextran long chain, and then cross-linked sulfopropyl group on the dextran molecule. This result reduces the steric hindrance effect between biomolecules and ligands and can greatly increase the dynamic loading of the target molecule.

2. Technical Characteristics

Appearance	White slurry, can be layered
Matrix	High-rigidity agarose with long dextran chain
Functional group	Sulfopropyl
Average particle size+	36~44μm
Ionic capacity	160~220μmol H⁺/mL packed resin
Dynamic binding capacity	> 100 mg lysozyme/mL packed resin
Max. pressure	0.5 MPa
Chemical stability	Stable in common aqueous buffers: 1M NaOH++, 6M GuHCl, 30% isopropyl alcohol, 70% ethanol Avoid contact with oxidizing agents, cationic detergents.
pH stability	3~14(CIP)，4~12(working)
Temperature tolerance	Working temperature:2~40℃, Can't freeze.
Storage+++	2~30℃, 20% ethanol with 0.2M NaAc or 2% benzyl alcohol with 0.2M NaAc
Recommend flow velocity	100~300cm/h

+ Average particle size is the accumulated resin particle size of packing volume distribution

++1M NaOH only be used for cleaning.

+++2% benzyl alcohol is only used for international transport or special requirements from customer

3. Order Information

Product	Code No.	Pack size
Diamond SP Mustang XL	AI313205	25mL
	AI313207	100mL
	AI313211	500mL
	AI313212	1L
	AI313213	5L
	AI313214	10L
	AI313215	20L
	AI313216	40L

Prepacked columns	Code No.	Pack size
EzFast SP Mustang XL	EI03821	1×1mL
	EI313251	5×1mL
	EI313203	1×5mL
	EI313253	5×5mL
EzScreen SP Mustang XL	EI03825	1×4.9mL
EzScreen SP Mustang XL	EI03835	5×4.9mL
EzLoad 16/10 SP Mustang XL	EI313204	1 pcs
EzLoad 26/10 SP Mustang XL	EI313206	1 pcs

Product	Code No.	Pack size
Diamond SP Mustang XL	AI313205	25mL
	AI313207	100mL
	AI313211	500mL
	AI313212	1L
	AI313213	5L
	AI313214	10L
	AI313215	20L
	AI313216	40L

Prepacked columns	Code No.	Pack size
EzFast SP Mustang XL	EI03821	1×1mL
	EI313251	5×1mL
	EI313203	1×5mL
	EI313253	5×5mL
EzScreen SP Mustang XL	EI03825	1×4.9mL
EzScreen SP Mustang XL	EI03835	5×4.9mL
EzLoad 16/10 SP Mustang XL	EI313204	1 pcs
EzLoad 26/10 SP Mustang XL	EI313206	1 pcs

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Strong Cation Exchange Resins