Diamond Q Mustang

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1. Introduction

Ion exchange chromatography(IEC)is a very effective method for the separation and purification of biomolecule. The method mainly relies on the interaction between positive and negative charges, and uses the charge properties and differences of different biological molecules under specific conditions to separate them. It has the characteristics of high load, good resolution, controllable condition and easy scale-up. It has been widely used in medicine, chemical industry, metallurgy, food and other fields.

IEC resin is composed of three parts: (1)Cross-linked agarose matrix, that has the characteristics of porous, hydrophilic and good chemical stability; through the modification to traditional agarose molecules, it has stronger mechanical properties, which is called high rigid agarose, namely Diamond matrix; (2)Functional groups fixed to the matrix, which are electrically charged groups, determine the properties of the IEC resin; (3)An ion (called an equilibrium ion) that has an opposite charge to the functional group and can be reversibly bound to the functional group.

Diamond Q Mustang is a strong anion exchange resin formed by coupling quaternary ammonium groups to fine-grained high-rigidity agarose microspheres. It has a higher resolution than Diamond Q and is suitable for polished or intermediate purification in the chromatography step.

2. Technical Characteristics

Appearance	White slurry, can be layered
Matrix	High rigidity agarose
Functional group	Quaternary amine group
Average particle size+	36~44μm
Ionic capacity	150~180μmol Cl^-/mL packed resin
Dynamic binding capacity	> 50 mg β -lactoglobulin/mL packed resin > 55mg BSA/mL packed resin
Max. pressure	0.5 MPa
Pressure flow velocity	≥450cm/h(0.5MPa ,BXK 100/500, H=20cm,20℃)
Chemical stability	Stable in common aqueous buffers: 1M NaOH++,1M HAC++,70% ethanol , 20% ethanol, 30% isopropyl alcohol, 6M GuHCl,8M Urea, 100mM thionol +25mM Tris pH8.5, 0.1M citric acid +8M urea +1M NaCl pH2.5, 0.1M citric acid +8M urea pH2.5; Avoid contact with oxidizing agents, cationic detergents.
pH stability	2~14 (CIP), 2~12(Working)
Temperature tolerance	Working temperature:2~40℃, Can't freeze.
Storage+++	2~30℃, 20% ethanol or 2% benzyl alcohol
Recommended flow velocity	100~300cm/h

+The average particle size is the cumulative resin particle size of the filler volume distribution.

++1M NaOH and 1M HAc only be used for cleaning.

+++2% benzyl alcohol is only used for international transport or special requirements from customer

3. Order Information

Product	Code No.	Pack size
Diamond Q Mustang	AI0171	25mL
	AI0172	100mL
	AI304211	500mL
	AI0173	1L
	AI0174	5L
	AI0175	10L
	AI304215	20L
	AI304216	40L

Prepacked columns	Code No.	Pack size
EzFast Q Mustang	EI01721	1×1mL
	EI304251	5×1mL
	EI304203	1×5mL
	EI304253	5×5mL
EzScreen Q Mustang	EI01725	1×4.9mL
EzScreen Q Mustang	EI01735	5×4.9mL
EzLoad 16/10 Q Mustang	EI304204	1 pcs
EzLoad 26/10 Q Mustang	EI304206	1 pcs

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Strong Anion Exchange Resins