Microcarriers serve as biological inert base in the cell culture process while providing robust and non-rigid substrate for agitation culturing of cells. Cells can efficiently adhere to the microcarriers surface via electrostatic force and Van der Waal’s force, which expands surface area for the adherence of cells, boosting productivity by reducing room required by cell culturing. Its similar density to saline facilitates the even suspension of cells, suitable for the growth of wide-range cells with high yields. It is applicable in the culturing of most established cell lines, as well as primary cells and normal diploid cell strains.