Diamond CD-S Strong Cation Exchange Resins-IEX Resins丨Bestchrom

Diamond CD-S

Product Characteristics

CEX resin based on agarose matrix
High rigid agarose beads, suitable for the efficient processing of large feedstock volume at high flow rate.
High binding capacity, high resolution: for purification of different samples, improved efficiency
Widely applicable in the intermediate purification and polishing of macro-biomolecules including mAb, BsAb , antibody fragments, ADC drugs and Fc fusion proteins.

Diamond Protein L

Novo-A Diamond

Description

Download

Reviews

1. Introduction

Ion exchange (IEX) chromatography is a very effective method for the separation and purification of biomolecule. The method mainly relies on the interaction between positive and negative charges, and uses the charge properties and number difference of biological molecules under specific conditions to separate them. It has the characteristics of high load, good resolution, easy to control and easy scale-up. It has been widely used in medicine, chemical industry, metallurgy, food and other fields.

Diamond CD-S is a strong cation exchange resin, obtained by cation ligands on the high rigidity agarose beads in small size. The small bead size provides resin with high binding capacity and high resolution, making it ideal for the intermediate stage and polishing of purification process.

2. Technical parameters

Appearance	White to slight yellow suspension
Matrix	High rigidity agarose
Functional group	Cation ligands
Average particle size⁺	~60μm
Dynamic binding capacity⁺⁺	＞100 mg IgG /mL resin
Max pressure	0.5MPa
Chemical stability	Common solutions: 1M NaOH⁺⁺⁺, 6M GuHCl, 30% isopropanol, 70% ethanol Avoid exposure to strong oxidants and cation exchange detergents
pH stability	3~14 (CIP), 4~12 (operation)
Operating temperature	2~40°C, do not freeze
Storage	2~30°C, 20% ethanol
Recommended flow rate	100~300cm/h

+Average particle size is the mean value of resin volume distribution accumulation.

++10%DBC,Buffer A:50mM Sodium acetate,pH5.5,10cm column , flow rate：100cm/h.

+++1M NaOH only used for washing.

3. Order information

Product	Cat. No.	Pack size
Diamond CD-S	AI05501	25mL
	AI05502	100mL
	AI05503	500mL
	AI05504	1L
	AI05505	5L
	AI05506	10L
	AI05507	20L

Pre-packed column	Cat. No.	Pack size
EzFast Diamond CD-S	EI05521	1×1mL
	EI05531	5×1mL
	EI05523	1×5mL
	EI05533	5×5mL
EzScreen Diamond CD-S	EI05525	1×4.6mL
EzScreen Diamond CD-S	EI05535	5×4.6mL
EzSelect Diamond CD-S	EI05526	8×600μL
EzLoad 16/10 Diamond CD-S	EI05501	1pcs
EzLoad 26/10 Diamond CD-S	EI05511	1pcs