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Strong Anion Exchange Resins

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Ion Exchange Resins
Strong Anion Exchange Resins

Diamond Q Mustang XL

Diamond Q Mustang XL

Product Characteristics

  • Anion exchange chromatography resin with high resolution, high binding capacity
  • High rigid, high resolution agarose beads, suitable for the intermediate purification and polishing of smaples on production scale
  • Good mechanical and chemical stability, long working life
  • Widely applicable in the purification of bio-molecules including proteins, nucleic acids and peptides.
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Description
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1. Introduction

Ion exchange (IEX) chromatography is a very effective method for the separation and purification of biomolecule. The method mainly relies on the interaction between positive and negative charges, and uses the charge properties and differences of different biological molecules under specific conditions to separate them. It has the characteristics of high load, good resolution, controllable condition and easy scale-up. It has been widely used in medicine, chemical industry, metallurgy, food and other fields.

IEX resin is composed of three parts: (1) Cross-linked agarose matrix, that has the characteristics of porous, hydrophilic and good chemical stability, through the modification and modification of traditional agarose molecules, it has stronger mechanical properties, which is called high rigid agarose, namely Diamond substrate. (2)Functional groups fixed to the matrix, which are electrically charged groups, determine the properties of the IEX resin. (3)An ion (called an equilibrium ion) that has an opposite charge to the functional group and can be reversibly bound to the functional group.

Diamond Q Mustang XL is a high-rigidity agarose microsphere first coupled with a long dextran chain, and then cross-linked quaternary amino groups on the dextran molecule. This structure reduces the steric hindrance effect between biomolecules and ligands, greatly increasing the DBC of target molecules.

 

2. Technical characteristics

Appearance

White slurry

Matrix

High-rigidity agarose with long dextran chain

Functional group

Quaternary amine group

Average particle size+

36~44μm

Ionic capacity

170-230 μmol Cl-/mL packed resin

Dynamic binding capacity

> 100mg BSA/ mL packed resin

Max. pressure

0.5MPa

Chemical stability

Stable in common aqueous buffers: 1M NaOH++, 6M GuHCl, 30% isopropyl alcohol, 70% ethanol

Avoid contact with oxidizing agents, cationic detergents.

pH stability

2~14(CIP), 2~12 (working)

Operating temperature

Operating temperature:2~40℃, do not freeze.

Storage+++

2~30℃,20% ethanol or 2% benzyl alcohol

Recommend flow velocity

100~300cm/h

 

+ Average particle size is the accumulated resin particle size of packing volume distribution.

++1M NaOH only be used for cleaning.

+++2% benzyl alcohol is only used for international transport or special requirements from customer.

 

3. Order information

Product

Cat. No.

Pack size

Diamond Q Mustang XL

AI314205

25mL

AI314207

100mL

AI314211

500mL

AI314212

1L

AI314213

5L

AI314214

10L

AI314215

20L

AI314216

40L

 

Prepacked columns

Cat. No.

Pack size

EzFast Q Mustang XL

EI03721

1×1mL

EI314251

5×1mL

EI314203

1×5mL

EI314253

5×5mL

EzScreen Q Mustang XL

EI03725

1×4.6mL

EI03735

5×4.6mL

EzLoad 16/10 Q Mustang XL

EI314204

1 pcs

EzLoad 26/10 Q Mustang XL

EI314206

1 pcs

 

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