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Strong Anion Exchange Resins

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Ion Exchange Resins
Strong Anion Exchange Resins

Q XL Big Beads

Q XL Big Beads

Product Characteristics

  • AEX resin with Big bead size(100~300μm) and high binding capacity.
  • Suitable for the rapid and efficient processing of large feedstock volume.
  • Good mechanical and chemical stability, long working life
  • Widely applicable in the rapid capture of highly viscous sample in downstream bio-processing.
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Description
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1. Introduction

Ion exchange (IEX) chromatography is a very effective method for separation and purification of biological molecules. The method mainly relies on the interaction between positive and negative charges, and uses the nature and difference of the charges carried by different biomolecules under specific conditions to separate. It has the characteristics of high load capacity, good resolution, controllable conditions and easy amplification. It has been widely used in medicine, chemical industry, metallurgy, food and other fields.

The ion exchange resin is composed of three parts: (1) Cross-linked mesh base frame, which is porous, hydrophilic and chemically stable. (2)The functional group fixed on the base frame, which is a charged group, determining the nature of the ion exchange chromatography resin. (3) An ion (called an equilibrium ion) that has an opposite charge to the functional group and can be reversibly bound to the functional group.

XL Big Beads series resin are obtained by firstly coupling linear dextran molecules on the large particle highly cross-linked agarose base, before coupling various functional groups to the dextran molecules. This structure reduces the steric hindrance among biomolecules and can greatly increase the binding with target molecules. The large particle base can tolerate samples with poor clarity, reducing the possibility of column blockage. Its fast flow velocity is suitable for processing large samples in a short time.

Q XL Big Beads is a strong anion exchange resin, which can directly capture biological macromolecules from the feed stock. It enjoys high binding capacity and fast flow velocity.

 

2. Technical characteristics

Appearance

White slurry

Matrix

highly cross-linked agarose with dextran chain

Functional group

Quaternary amine group

Particle size+

100~300μm

Ionic capacity

230~330μmol Cl-/mL packed resin

Max. pressure

0.3MPa

Chemical Stability

Stable in common aqueous buffers: 1M NaOH++,6M GuHCl, 70% ethanol , 30% Isopropyl alcohol

Avoid contact with oxidizing agents

pH stability

2~14(CIP), 2~12(working)

Operating temperature

Operating temperature:2~40℃, do not freeze.

Storage+++

2~30℃, 20% ethanol or 2% benzyl alcohol.

Recommended flow velocity

300~900cm/h

 

+Particle size is normally distributed, and particles within this range account for more than 95% of the total.

++1M NaOH only be used for cleaning.

+++2% benzyl alcohol is only used for international transport or special requirements from customer.

 

3. Order information

Product

Cat. No.

Pack size

Q XL Big Beads

AI0231

25mL

AI214407

100mL

AI0233

500mL

AI0234

1L

AI0235

5L

AI0236

10L

AI214415

20L

AI214416

40L

 

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