The majority of currently available insulin is obtained via genetic engineering synthesis and subsequent purification process, among which, chromatographic technology is most widely used.

As early as 1840s, scientists discovered cytoplasmic genetic factors which can metastasize among cells.

Binding capacity refers to the amount of target molecules a type of resin can bind under certain condition.

According to the list of top-selling drugs worldwide, antibody-based drugs play a dominant role in the market with an ever increasing demand in oncology sector.

After comparing sample purity before/after purification, it is found that AT Protein A Diamond Ultra can effectively remove impurities and improving purity of target antibody.

From June 10th to 14th, 2024, Bestchrom presented its innovative products at the ACHEMA 2024 exhibition in Germany.

On July 12th,2024, BIOPLUS-INTERPHEX KOREA 2024 took place at COEX Convention & Exhibition Center. Bestchrom global marketing team attended the event.

INTERPHEX 2024 event was held in Javits Center, NYC from 16th to 18th of April, 2024.

The established scientific proof helps to ensure the production of products which can consistently meet quality expectation.

Size exclusion resins are used in packing columns for size exclusion chromatography (SEC). Size exclusion resins contain pores of varying sizes and can be made by packing beads closely.

Host cell DNA (HCD) refers to the DNA fragments derived from host tissue cells of biologics. Therefore, HCD residue serves as a key link in the safety and quality control of biologics.

Antibody is complicated polymer structure, which presents heterogeneity in Mol.

Due to the risk of pathogen transmission, it is essential to remove or inactivate viruses to ensure the safety of biologics. Different biologics require specific process strategy.

Oligonucleotide drug, also known as small nucleic acid drug, is innovative drugs functioning based on the principle of complementary base pairing.

Being a major process-related impurity, HCP will significantly impact stability and efficacy of medicines due to its immunogenicity and proteolytic activity.

In the quest for effective downstream purification, various strategies emerge, encompassing protein engineering, process optimization, and choice of reagents.

Bispecific antibody(BsAb) is synthetic antibody which can simultaneously specifically bind with two antigens or epitopes via genetic recombination.

Color is an easily detectable indicator, so control and removal of pigments are critical steps in the protein production process.

Overall, the purification process of GLP-1 drugs is a complex and highly regulated process aimed at producing high-quality medications for the treatment of diabetes and obesity.

Collagen, as the most diversified structural and functional proteins, can be classified as mammalian and recombinant collagens