Oligonucleotide drug, also known as small nucleic acid drug, is innovative drugs functioning based on the principle of complementary base pairing.

Being a major process-related impurity, HCP will significantly impact stability and efficacy of medicines due to its immunogenicity and proteolytic activity.

In the quest for effective downstream purification, various strategies emerge, encompassing protein engineering, process optimization, and choice of reagents.

Bispecific antibody(BsAb) is synthetic antibody which can simultaneously specifically bind with two antigens or epitopes via genetic recombination.

Color is an easily detectable indicator, so control and removal of pigments are critical steps in the protein production process.

Overall, the purification process of GLP-1 drugs is a complex and highly regulated process aimed at producing high-quality medications for the treatment of diabetes and obesity.

Collagen, as the most diversified structural and functional proteins, can be classified as mammalian and recombinant collagens

Endotoxin is a major pyrogen substance in biological products, even a minor amount of which can cause inflammation, fever, vascular thrombosis, organ failure, shock and even death once entering into human body.

In vitro diagnostics (IVDs) play a vital role in modern healthcare, enabling accurate disease diagnosis, patient monitoring, and treatment decisions.

IVD can be categorized into biochemical diagnosis, immunodiagnosis, molecular diagnosis, point-of-care testing(POCT) and microbial diagnosis

Plasmid is loop superhelix double strand DNA, which is able to replicate and inherit in host cells independent of chromosomes.

The chromatographic technique achieves purification purposes via different physical & chemical properties of components in the mixture.

Chromatography resin plays a vital role in the purification of blood products, ensuring the removal of impurities and isolation of target molecules with high purity and efficiency.

Recombinant protein is proteins expressed in host cells. The modified protein is obtained by gene coding of target proteins via recombinant DNA technology before being introduced into the host cells.

Chromatography technology can effectively separate, purify and analyze vaccine components, ensuring that the final product meets strict quality and safety standards.

Chromatography techniques are used in areas such as pharmaceuticals, clinical trials, environmental and chemical safety, food and beverages, drug testing and molecular biology.

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The biggest advantage HIC resins enjoy is their mild interaction with proteins, which helps to keep the natural structure and bioactivity of macro-biomolecules to the greatest extent.

Chromatography resins can be categorized into affinity resin, ion exchange (IEX) chromatography resin, and hydrophobic interaction chromatography (HIC) resin, etc.

The 4th Bio-ONE Annual Bioprocess Industry Summit was successfully held from November 17th-November 18th in Shanghai. With a theme of technological innovation and in-process transformation,