In this article, an innovative Protein A based approach for the effective removal of aggregates will be shared and introduced.

Purification serves as a key step in the antibody drug production. Traditionally, ion exchange chromatography mainly relies on salt gradient for elution. In recent years, high liner pH gradient is showing better selectivity and purification effectiveness.

The purpose of this article is to introduce four chromatography methods in terms of separation principle, advantages, applicable scenarios and tips for resin selection, so as to promote your process development and technical understanding.

Mixed-mode chromatography (MMC), also known as multimodal chromatography, encompasses chromatographic techniques employing multiple types of interactions between the stationary phase and analytes to achieve efficient separation.

Chromatography resins can be categorized into affinity resin, ion exchange (IEX) chromatography resin, and hydrophobic interaction chromatography (HIC) resin, etc.

Comparability study serves as the foundation and key to the success of the pharmaceutical changes evaluation in biological products.

In addition to the specific enrichment of low abundance protein in complex condition, it can boost yields of target protein as well as bring new property to target proteins.

Bestchrom has successfully provided downstream purificiaiton solutions for multiple recombinant herpes zoster vaccines, including purification process development and allied resins.

In the field of biopharmaceuticals, formation of antibody aggregates has always been a challenge in the production of antibody drugs.

Pathogens and their metabolites can serve as an immunological formulation to prevent or treat infectious diseases in the manner of artificial attenuation, detoxification, inactivation, or genetic engineering methods

Various purification methods have been involved in the purification of blood products, among which cold ethanol fractionation is regarded as the basic method of large scale plasma purification.

Human Respiratory syncytial virus (RSV) is A non-segmental single-strand negative strand RNA virus. The virus belongs to paramyxoviridae, pneumovirus genus and pneumovirus subfamily.

Are you looking for an excellent chromatography resin manufacturer or supplier to serve you? This article will help you choose the right chromatography resin company.

Affinity chromatography resin is an important material specifically used in the affinity chromatography process. The resins used in affinity chromatography usually consist of a solid support matrix!

Chromatography media (also known as "chromatography resin" when used in the field of biological macromolecules) is the core key of liquid chromatography technology.

The article explores strategies for removing host cell proteins (HCP) in antibody drug production, focusing on techniques like affinity chromatography, depth filtration, and ion exchange chromatography. Optimizing these methods is crucial for ensuring drug stability and efficacy.

Bispecific antibody (BsAb) is a type of artificial antibody via gene recombination technology.

The appearance of the solution is a must test item for raw material used for injection, which usually includes the clarity, turbidity and color of liquid.

In R&D of bio-pharmaceuticals, rapid optimization of upstream and downstream process conditions, enhanced process efficiency and improved product quality have long been the core goals of R&D team.

Biological products using human or animal materials risk viral contamination from raw materials or additives during preparation and formulation stages.